Targeted Genome Sequencing

Overview:

Targeted Genome Sequencing is a genetic technique to sequence specific genomic regions, rather than the entire genome (as in Whole Genome Sequencing) or the whole exome (as in Whole Exome Sequencing). This method allows researchers and clinician to concentrate on specific genes, genomic regions, or variants of interest, making it a more cost-effective and focused approach for certain research or clinical applications.

Applications:

  • Identify genetic causes of rare and undiagnosed diseases in clinical setting.

  • Identify mutations in cancer-related genes, particularly in somatic mutations and germline mutations.

  • Investigating Mendelian diseases or conditions caused by mutations in a single gene or in a set of genes.

  • Identify genetic variants involving in an individual response to certain drugs, which is useful to develop personalized medicine strategies.

Panels Provided:

  • Focus Oncology panels: Comprehensive cancer, Breast cancer, Colorectal cancer, Brain cancer, Lung cancer, Myeloid Neoplasms

  • Hereditary Disease panels: Comprehensive Hereditary Carrier, CardioVascular Hereditary Panel, Parkinson’s, Alzheimer, Dementia Hereditary Panel, Cystic Fibrosis, Diabetes/Obesity Hereditary

  • Other commercial panels

  • Customized panel designed to individual lab requirement